Metastatic Bone Disease
DOI:
https://doi.org/10.31282/joti.v5n3.104Keywords:
clinical manifestations, metastatic bone disease, imaging studies, therapyAbstract
Bone metastases are frequent complication of carcinoma, occurring in approximately 70% of patients with advanced breast and prostate carcinomas, and 15-30% of patients with lung, colon, uterus, rectum, thyroid or kidney cancer approximately. Metastatic bone by tumor is a frequent cause of destructive lesions in mature bone. Osteolytic metastases induce spinal cord compression, other nerve compression, pathological fractures, hypercalcemia, and acute pain. For the identification, diagnosis, prognosis, therapy, and follow-up planning of bone metastases, imaging investigations are crucial. Imaging tests are useful for bone screening, describing metastases, and confirming their existence in individuals with non-skeletal malignancies. In patients with malignancy, the diagnosis of bone metastases is confirmed by radiography. If bone metastases are suspected, advanced imaging techniques may be required to confirm the diagnosis and locate the primary tumor. This article aims to review the clinical manifestations, advanced and imaging studies, and therapy of bone metastases in cancer.
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